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Updated: Apr 29, 2026

A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
Published on: February 2, 2021
ACR Appropriateness Criteria(®) on renal failure.
Erick M Remer1, Nicholas Papanicolaou2, David D Casalino3
1Cleveland Clinic, Cleveland, Ohio.
Imaging guidelines help determine the best kidney imaging tests for acute kidney injury and chronic kidney disease. Clinical context is crucial for selecting appropriate imaging like ultrasonography or CT scans.
Area of Science:
- Nephrology
- Radiology
- Medical Imaging
Background:
- Imaging is integral to managing acute kidney injury (AKI) and chronic kidney disease (CKD).
- The utility of imaging modalities is highly dependent on specific clinical scenarios and patient risk factors.
- Established guidelines aid in selecting appropriate imaging procedures.
Purpose of the Study:
- To outline the appropriate use of various imaging techniques in the evaluation of renal dysfunction.
- To emphasize the importance of clinical context in guiding imaging decisions for kidney disease.
- To highlight the role of evidence-based guidelines in optimizing imaging selection.
Main Methods:
- Review of current medical literature on renal imaging.
- Application of the American College of Radiology Appropriateness Criteria.
- Consensus-based methodology (modified Delphi) for rating imaging appropriateness.
- Consideration of expert opinion when evidence is limited.
Main Results:
- Ultrasonography is valuable for initial assessment of renal dysfunction, evaluating for reversible causes, and determining disease chronicity.
- Imaging is most beneficial for detecting urinary obstruction in high-risk patients or those with strong clinical suspicion.
- Advanced imaging like CT, MR arteriography, and ultrasound-guided biopsy are indicated for specific clinical situations.
Conclusions:
- The judicious use of imaging, guided by clinical presentation and evidence-based criteria, is essential for effective management of kidney disease.
- Ultrasonography serves as a primary tool for initial renal assessment.
- Specialized imaging techniques and biopsies are reserved for complex or specific diagnostic challenges.
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