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Updated: Apr 29, 2026

Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
Published on: March 1, 2013
Effect of size on biological properties of nanoparticles employed in gene delivery
Shashi Prabha1, Geeta Arya2, Ramesh Chandra3
1a Department of Pharmaceutical Chemistry , Jamia Hamdard University , New Delhi , India.
Context:
The size of nanoparticles plays a pivotal role in determining the gene delivery efficiency.
Objective:
A focus on the studies done to investigate the effect of nanoparticles size on biological aspects of gene delivery.
Methods:
A through literature survey has been done regarding studies done to investigate the effect of nanoparticles size on uptake, transfection efficiency and biodistribution has been cited in the present review.
Results And Conclusion:
The gene delivery efficacy may depend on conjugation of several factors such as the chemical structure of polymers, cell type, and nanoparticle size, composition and interaction with cells.
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