[Angiographic course of advanced ischemic cardiopathy]

Related Experiment Video

Updated: Oct 21, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

C Solórzano Martín1, J M Delgado Hurtado

  • 1Departamento de Cardiología, del Hospital de Especialidades, Guadalajara, Jalisco.

Archivos Del Instituto De Cardiologia De Mexico
|January 1, 1989
PubMed

Insights

Progression of coronary artery disease is linked to patient factors and disease extent. Deteriorating heart function can predict the need for repeat angiography in patients with coronary artery disease.

Area of Science:

  • Cardiology
  • Cardiovascular Medicine
  • Interventional Cardiology

Background:

  • Coronary artery disease (CAD) is a leading cause of mortality worldwide.
  • Understanding the progression of CAD is crucial for patient management and surgical planning.
  • Repeated angiographic assessment is used to monitor disease severity.

Purpose of the Study:

  • To investigate factors associated with the progression of coronary artery obstructions in patients with significant CAD.
  • To determine the relationship between coronary pathology progression and left ventricular function.
  • To assess the predictive value of non-invasive tests for the need for repeat angiography.

Main Methods:

  • Study included 30 patients with significant CAD awaiting surgery.
  • Repeated cineangiography was performed over a mean follow-up of 16 months.
  • Clinical, angiographic, and electrocardiographic factors were analyzed for association with disease progression.

Main Results:

  • Age, risk factors, angina progression, and electrocardiographic changes correlated with increased coronary obstructions.
  • Patients with one-vessel disease showed slower progression than those with multi-vessel involvement.
  • Collateral circulation increased with worsening coronary obstruction.
  • Progression of CAD was significantly associated with impaired left ventricular function, including reduced ejection fraction and increased segmental motility impairment (p < 0.05).

Conclusions:

  • Clinical and angiographic factors, along with disease extent, influence CAD progression.
  • Worsening coronary pathology directly impacts left ventricular function.
  • Non-invasive assessment of left ventricular contraction can predict the need for repeat coronary angiography.

More Related Videos

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction14:19

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis09:36

A Magnetic Resonance Imaging-based Computational Protocol for Analysis of Plaque Morphology and Hemodynamics in Patients with Carotid Artery Stenosis

Published on: August 12, 2025

Related Concept Videos

Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...