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Increase in desipramine serum levels associated with methadone treatment
I Maany1, V Dhopesh, I O Arndt
1Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia.
The American Journal of Psychiatry
|December 1, 1989
Abstract:
Five men in a methadone treatment program who were also receiving desipramine had significantly higher desipramine serum levels when taking both drugs than when taking the antidepressant alone. Monitoring of desipramine serum levels may be useful with such patients.