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A cerebellar tremor in a patient with human immunodeficiency virus-1 associated with progressive multifocal
Hee-Jin Kim1, Jae-Jung Lee1, Phil Hyu Lee1
1Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
Abstract:
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) caused by JC virus infection in oligodendrocytes, especially in patients with acquired immunodeficiency syndrome (AIDS). Movement disorders associated with PML are very rare. Here, we report a case of PML in an AIDS patient who presented with a cerebellar tremor, caused by lesions in the cerebellar outflow tract. A cerebellar tremor can be a rare clinical manifestation in patients with PML.
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