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Restlessness with Manic Episodes due to Right Parietal Infarction

Suk Yun Kang1, Jong Won Paik2, Young Ho Sohn2

  • 1Department of Neurology and Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea ; Department of Neurology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea.

Journal of Movement Disorders
|May 29, 2014
PubMed

Insights

Mood disorders are common after stroke, but mania is rare. This study reports a novel case of post-stroke mania linked to a right parietal lobe infarction, expanding understanding of these rare neurological events.

Area of Science:

  • Neurology
  • Neuropsychiatry

Background:

  • Mood disorders, including depression and anxiety, are frequent sequelae of acute stroke.
  • Restlessness with manic episodes following stroke is an uncommon but significant clinical presentation.

Purpose of the Study:

  • To report a rare case of post-stroke mania associated with a right parietal lobe infarction.
  • To review existing literature on lesions implicated in post-stroke mania.
  • To contribute to understanding the neurobiological mechanisms of mania after stroke.

Main Methods:

  • Case report of a patient experiencing restlessness with manic episodes after acute stroke.
  • Literature review of reported cases of post-stroke mania and associated lesion locations.

Main Results:

  • The patient presented with restlessness and manic episodes following an acute infarction in the right parietal lobe.
  • Previous reports indicate that lesions in the thalamus, caudate nucleus, and temporal and frontal lobes can precipitate post-stroke mania.

Conclusions:

  • Right parietal lobe infarction is a novel location associated with post-stroke mania.
  • This case highlights the diverse neuroanatomical substrates that can underlie mania after stroke.
  • Further research is needed to elucidate the specific pathways involved in post-stroke manic presentations.
Keywords:
MRIManiaPETRestlessnessStroke

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