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Updated: Apr 29, 2026

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

Published on: April 26, 2019

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Development of Frequency of Stools over Time in Children with Hirschsprung Disease Posttransanal Endorectal One-Stage

Christina Granéli1, Pernilla Stenström1, Anna Börjesson1

  • 1Department of Pediatric Surgery, Skane University Hospital, Lund, Sweden.

European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [Et Al] = Zeitschrift Fur Kinderchirurgie
|May 30, 2014
PubMed

Insights

It takes four years after the transanal endorectal one-stage pull-through (TERPT) for children with Hirschsprung disease (HD) to achieve normalized bowel movements. This study tracked stool frequency post-TERPT to set realistic family expectations.

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Clinical Outcomes Research

Background:

  • The transanal endorectal one-stage pull-through (TERPT) is a common surgical procedure for Hirschsprung disease (HD) in children.
  • Understanding post-operative outcomes is crucial for managing patient expectations and planning care.

Purpose of the Study:

  • To assess the daily stool frequency in children following a one-stage TERPT procedure for Hirschsprung disease.
  • To establish a timeline for functional recovery after TERPT.

Main Methods:

  • A prospective follow-up study was conducted from 2005 to 2012.
  • Data on stool frequency were collected from patients undergoing TERPT.
  • A control group of age and gender-matched children was used for comparison.

Main Results:

  • Initially, patients had a median of 12 stools/day, decreasing to a median of 4 stools/day after 1 year.
  • By 4 years post-TERPT, the number of stools per day was not significantly different from healthy controls.
  • The study highlights a significant recovery period following the procedure.

Conclusions:

  • Normalization of stool frequency after TERPT for Hirschsprung disease takes approximately 4 years.
  • Standardized reporting of stool frequency, incontinence, and constipation is recommended for long-term outcome assessment.
  • This research provides valuable insights for families and clinicians managing children post-TERPT.
Abstract

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