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Updated: Apr 29, 2026

A Tuberculosis Molecular Bacterial Load Assay TB-MBLA
Published on: April 30, 2020
The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to
Isobella Honeyborne1, Bariki Mtafya2, Patrick P J Phillips3
1Centre for Clinical Microbiology, Department of Infection, University College London, London, United Kingdom i.honeyborne@ucl.ac.uk.
Abstract:
We evaluated the use of the molecular bacterial load (MBL) assay, for measuring viable Mycobacterium tuberculosis in sputum, in comparison with solid agar and liquid culture. The MBL assay provides early information on the rate of decline in bacterial load and has technical advantages over culture in either form.
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