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Related Experiment Videos

Orbital tumors in children.

J D Bullock1, S H Goldberg, S M Rakes

  • 1Department of Ophthalmology, Wright State University School of Medicine, Dayton, Ohio 45409.

Ophthalmic Plastic and Reconstructive Surgery
|January 1, 1989
PubMed
Summary

This study analyzed 1,370 pediatric orbital tumors, finding cystic and vasculogenic types most common. Clinically-based series show a lower malignancy rate than referral center studies.

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Area of Science:

  • Ophthalmology
  • Pediatric Oncology
  • Pathology

Background:

  • Numerous reviews on pediatric orbital tumors exist, often from pathology referral centers or large institutions.
  • Tumor distribution in existing series can be biased by the evaluating facility's nature and geographic location.

Purpose of the Study:

  • To analyze a clinically based series of pediatric orbital tumors.
  • To compare findings with existing literature, accounting for potential biases in reported tumor types and incidence.

Main Methods:

  • Analysis of 141 pediatric orbital tumors from a clinical series.
  • Review of 9 additional series totaling 1,229 cases for an aggregate of 1,370 cases.
  • Comparison of tumor incidence and types between the clinical series and combined literature data.

Main Results:

  • The clinical series reported a 10.6% incidence of malignant lesions.
  • This rate is significantly lower than the 24% incidence reported in combined referral center/pediatric hospital studies.
  • Cystic and vasculogenic orbital tumors were the most frequent, comprising 58% of the clinical series and 40% of the combined series.

Conclusions:

  • Clinically based series may offer a less biased perspective on the incidence of malignant pediatric orbital tumors.
  • Cystic and vasculogenic tumors represent the predominant types of orbital lesions in children.
  • Awareness of reporting biases is crucial when interpreting literature on pediatric orbital tumors.

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