Non-hodgkin's lymphoma and work in agriculture: Results of a two case-control studies in Saskatchewan, Canada
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Updated: Apr 28, 2026

Application of Long-term cultured Interferon-γ Enzyme-linked Immunospot Assay for Assessing Effector and Memory T Cell Responses in Cattle
Published on: July 11, 2015
Chandima P Karunanayake1, James A Dosman1, Punam Pahwa2
1Canadian Centre for Health and Safety in Agriculture, University of Saskatchewan, 104 Clinic Place, PO Box 23, Saskatoon, Saskatchewan, S7N 5E5, Canada.
Objectives:
The objective was to examine the association between non-Hodgkin's lymphoma (NHL) and farming-related activities, gender, pesticides exposure, and exposure to chemicals other than pesticides in Saskatchewan.
Materials And Methods:
Male and female study participants were taken from two separate case-control studies conducted in Saskatchewan province, Canada. A case was defined as any man or woman aged 19 years and older with a first diagnosis of NHL registered by the Saskatchewan Cancer Agency during the study period. Conditional logistic regression was used to fit the statistical models.
Results:
Farming exposure and exposure to pesticides-contaminated cloths were related to an increased risk of NHL. Exposure to pesticides was strongly associated with an increased risk of NHL, especially for men.
Conclusion:
For men, the incidence of NHL was associated with exposure to pesticides after adjusting for other independent predictors.
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