Targeting human equilibrative nucleoside analog transporter (hENT1) expression through modified low glycemic index
Valerio Pazienza1, Alessandro Del Nobile Matteo2
1Gastroenterology Unit, IRCCS "Casa Sollievo della Sofferenza" Hospital, San Giovanni Rotondo, FG, Italy; Department of Agricultural Sciences, Food and Environment, University of Foggia, FG, Italy.
Abstract:
Pancreatic cancer is a highly aggressive and chemotherapy-resistant cancer. Up to date, the primary goals of nutrition interventions for pancreatic cancer' patients are to prevent or reverse loss of weight and malnutrition in order to maintain dose and schedule of cancer treatments and/or to manage symptoms due to the lack of enzymes' production by the damaged pancreas. With this script, we sought to underline the potential link between dietary settings and the modulation of chemoresistance in pancreatic cancer.
