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Updated: Apr 28, 2026

Isolation of Primary Human Colon Tumor Cells from Surgical Tissues and Culturing Them Directly on Soft Elastic Substrates for Traction Cytometry
Published on: June 4, 2015
The soft underbelly of tumor cells
Yufeng Shi1, S Kyun Lim1, Luis F Parada1
1Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Abstract:
In a recent Cell paper, Kitambi and colleagues identify a small molecule (Vacquinol-1) that has beneficial effects on a glioblastoma multiforme mouse model by oral administration. In glioblastoma cells, Vacquinol-1 targets macropinocytosis, a cellular process that will not lead to cell death in normal cells.
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