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KCNH2 polymorphism and methadone dosage interact to enhance QT duration

Aline Hajj1, Kamilia Ksouda2, Katell Peoc'h3

  • 1INSERM UMR-S 1144, Variabilité de la Réponse aux Psychotropes, Université Paris Descartes, Université Paris Diderot, PRES Sorbonne Paris Cité, Hôpital Fernand Widal, 200 rue du Fg St Denis, 75010 Paris, France; AP-HP, Hôpital Lariboisière, Service de Biochimie et Biologie moléculaire, 2 rue Ambroise Paré, 75010 Paris, France; Pharmacology Unit, Pharmacokinetics and Clinical Pharmacy, Faculty of Pharmacy, Saint Joseph University, Beirut, Lebanon.

Drug and Alcohol Dependence
|May 31, 2014
PubMed
Abstract

Keywords:
ChannelopathiesMethadoneQT intervalRepolarization reserve

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