Present status and future concerns of expanded newborn screening in malaysia: sustainability, challenges and

Yin Hui Leong1, Chee Yuen Gan1, Mohd Adi Firdaus Tan1

  • 1Centre for Advanced Analytical Toxicology Services, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia.

Insights

Newborn screening (NBS) programs are vital for early diagnosis and treatment of lifelong impairments. Implementing expanded NBS in developing nations faces significant challenges, hindering its national adoption and public health benefits.

Area of Science:

  • Public Health
  • Pediatrics
  • Genetics

Background:

  • Newborn screening (NBS) is a key World Health Organization strategy for preventing congenital anomalies and improving child health.
  • Despite its importance, NBS implementation is slow and challenging in developing countries, particularly in South-East Asia and North Africa.
  • Expanded NBS is not mandatory and not integrated into the public healthcare system in many regions.

Purpose of the Study:

  • To highlight the challenges in establishing a national newborn screening program.
  • To emphasize the need for policy maker involvement in successful NBS implementation.

Main Methods:

  • This study is a review of the current status and challenges of newborn screening programs.
  • Analysis of factors hindering NBS implementation in developing countries.

Main Results:

  • Key challenges include limited funding, manpower shortages, inadequate support services, low public awareness, and uncertain healthcare practitioner commitment.
  • Expanded NBS is not yet a mandatory public healthcare component in many countries.

Conclusions:

  • Successful national NBS programs require policy maker support and public engagement.
  • Addressing identified challenges is crucial for expanding NBS benefits to all populations.

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