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Current Status of Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction and Multivessel
Min Chul Kim1, Myung Ho Jeong1, Sang Hyung Kim1
1Department of Cardiovascular Medicine, Heart Center, Chonnam National University Hospital, Gwangju, Korea.
Insights
For ST-elevation myocardial infarction (STEMI) patients with multivessel disease, this review examines the benefits and risks of complete revascularization during primary percutaneous coronary intervention (PCI) versus treating only the culprit artery.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Acute Coronary Syndromes
Background:
- Primary percutaneous coronary intervention (PCI) is standard for ST-segment elevation myocardial infarction (STEMI).
- Multivessel coronary artery disease (CAD) is found in ~50% of STEMI patients undergoing primary PCI.
- Optimal revascularization strategy in STEMI with multivessel CAD remains debated.
Purpose of the Study:
- To review the current evidence on multivessel PCI in STEMI patients.
- To discuss the risks and benefits of complete versus culprit-only revascularization.
- To propose an optimal revascularization strategy.
Main Methods:
- Literature review of previous studies on multivessel PCI in STEMI.
- Analysis of clinical outcomes comparing different revascularization strategies.
- Consideration of patient factors like cardiogenic shock and myocardial viability.
Main Results:
- Revascularization of the infarct-related artery alone is effective for STEMI.
- Studies show efficacy for multivessel PCI, either primary or staged.
- Clinical decision-making requires careful assessment of risks and benefits.
Conclusions:
- Multivessel PCI in STEMI requires individualized strategies.
- Consideration of cardiogenic shock and myocardial viability is crucial.
- Optimal strategy balances complete revascularization with procedural risks.
Abstract:
Primary percutaneous coronary intervention (PCI) is a standard interventional treatment modality for ST-segment elevation myocardial infarction (STEMI). Diagnostic coronary angiogram during PCI reveals multivessel coronary artery disease in about half of patients with STEMI, and it is difficult to make decision on the extent of intervention in these patients. Although revascularization for the infarct-related artery only is still effective for STEMI patients, several studies have reported the efficacy of multivessel revascularization during primary PCI, as well as in a staged PCI procedure. Clinicians should consider clinical aspects such as initial cardiogenic shock and myocardial viability when performing primary multivessel intervention, including the risks and benefits of multivessel revascularization in patients undergoing primary PCI. This review describes the current status of performing multivessel PCI in patients with STEMI and proposes an optimal revascularization strategy based on the previous literature.
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