Retinal hamartoma in childhood

Characteristic clinic details of two children affected with pigment-containing tumefactions of the posterior pole are described. The lesion although provisionally regarded as hamartomatous can, as in these two patients, exhibit inflammatory signs which may suggest a reactive inflammatory pathogenesis. Most tests are non-contributory, but fluorescence angiography and electro-oculography are of value in differential diagnosis. The former investigation has indicated that the pattern and intensity of vascular leakage in the mass may change over a period of a year.