A stereoselective ring-closing glycosylation via nonglycosylating pathway
1Department of Chemistry, The University of Hong Kong , Pokfulam Road, Hong Kong, PR China.
Abstract:
Two glycosyl partners were first coupled with as ester linkage, which upon reductive acetylation produced an α-acetoxy ether group. The subsequent activation with TfOH triggered the ring-closing process and provided the corresponding glycosidic bond in high β-selectivity without relying on neighboring group participation.
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