[Severe pneumonia due to cytomegalovirus in chronic obstructive pulmonary disease]
C Bosc1, M Clement2, A Deroux3
1Clinique universitaire de pneumologie, hôpital Albert-Michallon, CHU de Grenoble, BP 217, 38043 Grenoble cedex 09, France.
Unlabelled:
Severe pneumonia due to cytomegalovirus in chronic obstructive pulmonary disease.
Introduction:
We describe two cases of immunocompetent patients with chronic obstructive pulmonary disease (COPD) who developed severe cytomegalovirus (CMV) pneumonia. The clinical and radiological context and CMV replication in broncho-alveolar lavage suggested a diagnosis of CMV pneumonia.
Case Histories:
We report two cases in patients with moderate chronic obstructive pulmonary disease not treated with long-term steroid therapy who developed bilateral pneumonia with hypoxaemia. The only pathogen identified was CMV with replication of the virus in the broncho-alveolar lavage. Investigation failed to detect any associated immune deficiency.
Conclusion:
Severe cytomegalovirus pneumonia could be encouraged by the existence of chronic obstructive pulmonary disease due to local inflammatory changes.
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