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Updated: Apr 28, 2026

Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
[Intrapericardial lung cancer metastases: Is a curative approach feasible?]
M Riquet1, C Rivera1, P Mordant1
1Service de chirurgie thoracique, hôpital européen Georges-Pompidou, université Paris Descartes, 20-40, rue Leblanc, 75015 Paris, France.
Introduction:
Lung cancer metastases are classified M1a and M1b. Studies on patients with pleural invasion graded M1a have demonstrated the possibility of prolonged survival following multimodality treatment, but this has not been reported for M1a pericardial involvement.
Case Report:
A 59-year-old man underwent lung surgery for a poorly differentiated adenocarcinoma TTF1+ with K-ras mutation. He was staged as pT4N0 because of a nodule in another ipsilateral lobe. A pericardial effusion with imminent tamponade occurred during the postoperative course necessitating drainage leading to the discovery of pericardial metastases and restaging as pT4N0M1a. Adjuvant treatment was performed and the patient remains alive and disease free 3 years later.
Conclusions:
Management of pericardial M1a might be refined as has been the case in pleural M1a disease. Biological data might allow more precise classification and treatment. N0-N1 and non-T3-T4 by invasion patients might in selected cases benefit from surgery included as part of multimodal therapy.

