Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

HLA-alloimmunization in pregnancy.

U Bellati1, A Liverani, G Noia

  • 1Clinica Ostetrica Ginecologica, Università di Chieti, Italia.

Fetal Therapy
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Detection of Dengue virus RNA in Wastewater during a Local Epidemic in Central Italy (August-October 2024).

Food and environmental virology·2025
Same author

Trisomy 18 and the possibility of choice: The importance of Perinatal Hospice's support.

European journal of pediatrics·2025
Same author

Emergency Treatment of Cervical Vertebromedullary Trauma: 10 Years of Experience and Outcome Evaluation.

Acta neurochirurgica. Supplement·2023
Same author

Preliminary data on the neurophysiological evaluation of male sexual dysfunction in patients with pelvic ring fractures: a multicenter retrospective study.

European review for medical and pharmacological sciences·2023
Same author

The effect of combined drug therapy in lateral fragility fractures of the femur: a prospective observational study.

European review for medical and pharmacological sciences·2022
Same author

Proximal humerus fractures treatment in adult patients with bone metastasis.

European review for medical and pharmacological sciences·2022
Same journal

Ethical issues in prenatal diagnosis and fetal therapy: a Catholic perspective.

Fetal therapy·1989
Same journal

The rights of the embryo and the fetus.

Fetal therapy·1989
Same journal

Prevention and treatment of fetal lung immaturity.

Fetal therapy·1989
Same journal

Genetic correction of hereditary disease.

Fetal therapy·1989
Same journal

Selective birth in a dyzygotic twin pregnancy with discordancy for Down's syndrome.

Fetal therapy·1989
Same journal

First trimester maternal serum lysosomal enzymes: implications for carrier testing and prenatal diagnosis.

Fetal therapy·1989
See all related articles

The presence of anti-human leukocyte antigen (HLA) antibodies is linked to adverse perinatal outcomes. This contradicts previous findings suggesting a protective role against abortion, highlighting new concerns for fetal and neonatal health.

Area of Science:

  • Immunology
  • Obstetrics
  • Neonatology

Background:

  • Anti-human leukocyte antigen (HLA) antibodies are known to play a role in pregnancy.
  • Existing literature suggests a protective effect of anti-HLA antibodies against spontaneous abortion.
  • The impact of anti-HLA antibodies on other fetal and neonatal outcomes requires further investigation.

Purpose of the Study:

  • To analyze the correlation between the presence of anti-HLA antibodies and fetal neonatal problems.
  • To investigate potential associations beyond spontaneous abortion.

Main Methods:

  • Retrospective analysis of patient data.
  • Detection and quantification of anti-HLA antibodies.
  • Assessment of fetal and neonatal complications.

Related Experiment Videos

Main Results:

  • A significant correlation was observed between the presence of anti-HLA antibodies and perinatal problems.
  • This finding contrasts with some existing literature regarding abortion.
  • Specific adverse fetal and neonatal outcomes associated with anti-HLA antibodies were identified.

Conclusions:

  • The presence of anti-HLA antibodies is associated with increased risks of perinatal complications.
  • Further research is needed to elucidate the mechanisms underlying these associations.
  • Clinical monitoring for anti-HLA antibodies may be warranted in pregnancies at risk.