Related Experiment Video
Updated: Apr 28, 2026

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
[Clinical case of malignant pericardial mesothelioma]
Abstract:
We present a clinical case of pericardial mesothelioma diagnosed in vivo in a 45 years old patient. Pericardial mesothelioma developed asymptomatically and manifested after viral respiratory infection with a clinical picture of exudative pericarditis and progressive heart failure. Mesothelioma was eventually diagnosed but the patient died. Prevalence of primary pericardial mesothelioma, its risk factors, and criteria for diagnosis are also discussed.
Insights
This case study details a rare pericardial mesothelioma diagnosed in a 45-year-old patient. The rare cancer developed asymptomatically, leading to heart failure and a fatal outcome despite diagnosis.
Area of Science:
- Oncology
- Cardiology
- Pathology
Background:
- Primary pericardial mesothelioma is a rare malignancy.
- Its etiology and risk factors remain incompletely understood.
- Diagnosis often presents challenges due to its rarity and variable presentation.
Observation:
- A 45-year-old patient presented with symptoms following a viral respiratory infection.
- Clinical manifestations included exudative pericarditis and progressive heart failure.
- The patient's condition ultimately led to a diagnosis of pericardial mesothelioma.
Findings:
- The case highlights the asymptomatic development of pericardial mesothelioma.
- Viral infections may potentially trigger or unmask the condition.
- Despite diagnosis, the patient succumbed to the disease, underscoring its aggressive nature.
Implications:
- This case emphasizes the need for increased awareness of rare pericardial tumors.
- Further research into the prevalence and risk factors of pericardial mesothelioma is warranted.
- Diagnostic criteria and treatment strategies for this rare condition require further refinement.
Related Concept Videos
Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis I: Introduction
Pleural Disorders: Types and Brief Description
Pericarditis III: Medical Management
Pericarditis IV: Nursing Management
Mitral Stenosis II: Clinical features and Diagnostic Tests

