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Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
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Related Experiment Video

Updated: Apr 28, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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Measuring the burden: alcohol's evolving impact.

Ralph Hingson, Jürgen Rehm

    Alcohol Research : Current Reviews
    |June 3, 2014
    PubMed
    Summary

    Accurately measuring alcohol

    Area of Science:

    • Public Health
    • Epidemiology
    • Alcohol Research

    Background:

    • Alcohol consumption significantly impacts public health, contributing to morbidity and mortality.
    • Accurate measurement of alcohol exposure and its associated risks is crucial for understanding disease burden.

    Purpose of the Study:

    • To review factors complicating the measurement of alcohol's impact on health.
    • To provide an overview of current research on alcohol's role in disease burden.
    • To highlight research on alcohol consumption, alcohol-related morbidity and mortality, and alcohol use disorders.

    Main Methods:

    • Literature review of factors influencing measurement.
    • Overview of articles in a special issue on alcohol research.
    • Synthesis of research on alcohol consumption estimation.

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  • Analysis of alcohol-related morbidity and mortality data.
  • Examination of alcohol use disorder burden.
  • Main Results:

    • Several complicating factors hinder accurate measurement of alcohol's health impact.
    • Current research addresses estimation of alcohol consumption across demographics.
    • Studies investigate alcohol-related morbidity and mortality.
    • The burden of alcohol use disorders is a key research area.

    Conclusions:

    • Accurate measurement is essential but challenging.
    • This special issue consolidates current research on alcohol's public health impact.
    • Further research is needed to refine measurement and understand alcohol's role in disease.