Outcomes of children with abdominal compartment syndrome

Insights

Abdominal compartment syndrome (ACS) significantly increases mortality risk in critically ill children. Intra-abdominal pressure (IAP) monitoring and PRISM scores can help identify children at risk for developing ACS.

Area of Science:

  • Pediatric Critical Care Medicine
  • Intensive Care Medicine
  • Abdominal Compartment Syndrome Research

Background:

  • Abdominal compartment syndrome (ACS) is a critical condition with high mortality, yet poorly described in pediatric intensive care.
  • Understanding ACS in children is crucial for improving outcomes in critical care settings.

Purpose of the Study:

  • To determine the incidence of ACS in critically ill pediatric patients.
  • To evaluate the impact of ACS on mortality and pediatric intensive care unit (PICU) length of stay (LOS).
  • To identify predictors for mortality and ACS development in this population.

Main Methods:

  • Intra-abdominal pressures (IAP) were monitored in critically ill pediatric patients (<50 kg, mechanically ventilated, with urethral catheter) using the intra-vesical technique.
  • ACS was defined as IAP >12mmHg with new organ dysfunction.
  • Demographics, organ dysfunction measures, PICU LOS, and mortality were recorded.

Main Results:

  • ACS occurred in 4.7% of eligible pediatric patients, with a 50% mortality rate compared to 8.2% in non-ACS patients.
  • Intra-abdominal pressure (IAP) and ACS were independent predictors of mortality.
  • Elevated IAP and a PRISM score ≥17 predicted the development of ACS.

Conclusions:

  • Abdominal compartment syndrome (ACS) is a significant risk factor for mortality in critically ill children.
  • Intra-abdominal pressure (IAP) monitoring and PRISM scores can aid in identifying pediatric patients at risk for developing ACS.
Abstract

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