Outcomes of children with abdominal compartment syndrome
Insights
Abdominal compartment syndrome (ACS) significantly increases mortality risk in critically ill children. Intra-abdominal pressure (IAP) monitoring and PRISM scores can help identify children at risk for developing ACS.
Area of Science:
- Pediatric Critical Care Medicine
- Intensive Care Medicine
- Abdominal Compartment Syndrome Research
Background:
- Abdominal compartment syndrome (ACS) is a critical condition with high mortality, yet poorly described in pediatric intensive care.
- Understanding ACS in children is crucial for improving outcomes in critical care settings.
Purpose of the Study:
- To determine the incidence of ACS in critically ill pediatric patients.
- To evaluate the impact of ACS on mortality and pediatric intensive care unit (PICU) length of stay (LOS).
- To identify predictors for mortality and ACS development in this population.
Main Methods:
- Intra-abdominal pressures (IAP) were monitored in critically ill pediatric patients (<50 kg, mechanically ventilated, with urethral catheter) using the intra-vesical technique.
- ACS was defined as IAP >12mmHg with new organ dysfunction.
- Demographics, organ dysfunction measures, PICU LOS, and mortality were recorded.
Main Results:
- ACS occurred in 4.7% of eligible pediatric patients, with a 50% mortality rate compared to 8.2% in non-ACS patients.
- Intra-abdominal pressure (IAP) and ACS were independent predictors of mortality.
- Elevated IAP and a PRISM score ≥17 predicted the development of ACS.
Conclusions:
- Abdominal compartment syndrome (ACS) is a significant risk factor for mortality in critically ill children.
- Intra-abdominal pressure (IAP) monitoring and PRISM scores can aid in identifying pediatric patients at risk for developing ACS.
Introduction:
Abdominal compartment syndrome (ACS) is a problem across all critical care scenarios and is associated with a high mortality. It has not been well described in pediatric populations.
Objective:
To describe the occurrence of ACS in a subset of critically ill pediatric patients and determine its effects on mortality and length of pediatric intensive care stay (PICU LOS). We also aimed to find predictors of mortality and development of ACS.
Setting:
25 bed tertiary pediatric intensive care unit.
Patients:
PATIENTS less than 50 kg on mechanical ventilation and a urethral catheter.
Measurements:
Intra-abdominal pressures (IAP) were monitored using the intra-vesical technique. ACS was defined as IAP of >12mmHg associated with new organ dysfunction or failure. Demographics, physiologic measures of organ dysfunction, PICU LOS and mortality were monitored.
Main Results:
14 (4.7%) of 294 eligible patients had ACS. Mortality was 50% among those with ACS versus 8.2% without (p<.001). PICU LOS stay did not differ between groups. No difference in mortality or PICU LOS was seen in primary versus secondary ACS or in patients who underwent abdominal decompression compared to those without decompression. IAP and ACS were independent predictors of mortality (odds ratio 1.53, 95% CI, 1.17 - 1.99 and 9.09, 95% CI, 1.07 - 76.84) respectively. IAP and a PRISM score of ≥17 were predictive of developing ACS.
Conclusions:
ACS is a clinical problem that increases the risk of mortality in critically ill children. IAP and PRISM scores may help identify children likely to develop ACS.
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