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Updated: Aug 2, 2026
The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Outcomes research in psoriasis and psoriatic arthritis using large databases and research networks: a report from the
April W Armstrong1, Joel M Gelfand2, Amit Garg2
1From the Department of Dermatology, University of Colorado, Denver, Colorado; University of Pennsylvania, Perelman School of Medicine, Philadelphia, Pennsylvania; and the Department of Dermatology, Hofstra North Shore LIJ School of Medicine, Hempstead, New York, USA.A.W. Armstrong, MD, MPH, Vice Chair for Clinical Research, Associate Professor of Dermatology, Director, Dermatology Clinical Trials and Outcomes, Director, Psoriasis Care and Research, Department of Dermatology, Colorado Health Outcomes Program, University of Colorado Denver, School of Medicine; J.M. Gelfand, MD, MSCE, University of Pennsylvania, Perelman School of Medicine; A. Garg, MD, Associate Professor, Department of Dermatology, Hofstra North Shore LIJ School of Medicine. aprilarmstrong@post.harvard.edu.
Abstract:
Advances in healthcare informatics have increased the ability to address real-world, clinically relevant questions using large databases. When examining data sources, researchers and clinicians need to consider data validity, potential sources of misclassification, whether the source is sufficiently powered to detect clinically relevant differences, ability to obtain longitudinal data, containment of patients within a database, and ability to obtain structured point-of-care data. Population-based databases create opportunities for characterizing natural history of psoriatic diseases, conducting comparative effectiveness research, determining comorbidities, and providing epidemiology-based rational approaches to mechanistic investigations. Herein, we discuss the major data sources for clinical research in psoriasis, including electronic medical records, research networks, disease registries, and others.
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