Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Steps in the Modeling Process01:14

Steps in the Modeling Process

860
Albert Bandura's theory of observational learning identifies four critical processes: attention, retention, motor reproduction, and reinforcement or motivation.
Attention is the first necessary component for observational learning. It involves focusing on what the model is doing and saying. For example, if you decide to take a drawing class to enhance your skills, you need to pay close attention to the instructor's words and hand movements. The characteristics of the model significantly...
860
Modeling in Therapy01:26

Modeling in Therapy

823
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
823
Mechanistic Models: Overview of Compartment Models01:21

Mechanistic Models: Overview of Compartment Models

587
Mechanistic models, a category encompassing both physiological and compartmental modeling, differ from empirical models' approaches to incorporating known factors about the systems being modeled. Empirical models describe data with minimal assumptions, while mechanistic models aim to provide a robust description of available data by specifying assumptions and integrating known factors about the system. Compartmental analysis is a key example of a mechanistic model in pharmacokinetics and...
587
Multicompartment Models: Overview01:14

Multicompartment Models: Overview

712
Multicompartment models are mathematical constructs that depict how drugs are distributed and eliminated within the body. They segment the body into several compartments, symbolizing various physiological or anatomical areas connected through drug transfer processes such as absorption, metabolism, distribution, and elimination.
These models offer a more comprehensive representation of drug behavior in the body than one-compartment models. They accommodate the complexity of drug distribution,...
712
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving01:29

Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving

438
Mechanistic models play a crucial role in algorithms for numerical problem-solving, particularly in nonlinear mixed effects modeling (NMEM). These models aim to minimize specific objective functions by evaluating various parameter estimates, leading to the development of systematic algorithms. In some cases, linearization techniques approximate the model using linear equations.
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
438
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

359
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
359

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Distribution of Family Sizes Under a Time-Homogeneous Birth and Death Process.

Communications in statistics: theory and methods·2013
Same author

Pseudomembranous colitis in a pregnant woman.

Kathmandu University medical journal (KUMJ)·2012
Same author

Congenital varicella syndrome: the evidence for secondary prevention with varicella-zoster immune globulin.

CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne·2011
Same author

Pancreatic mucinous cystadenoma.

Tropical gastroenterology : official journal of the Digestive Diseases Foundation·2008
Same author

Applications of the concepts of affinity and distance to population problems.

Journal of biosocial science·1974
Same author

AN APPROXIMATE METHOD OF ANALYSIS FOR A TWO-WAY LAYOUT.

Biometrics·1965
Same journal

Bayesian Analysis of Longitudinal Ordinal Data with Missing Values Using Multivariate Probit Models.

Journal of statistics applications & probability·2025
See all related articles

Related Experiment Video

Updated: Apr 28, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

21.2K

A Pathway Idea for Model Building.

A M Mathai1, Panagis Moschopoulos2

  • 1McGill University, Canada and Centre for Mathematical Sciences, India.

Journal of Statistics Applications & Probability
|June 3, 2014
PubMed
Summary
This summary is machine-generated.

This study explores mathematical and stochastic models that transition between functional forms using pathway parameters. These flexible models can approximate data across various scientific fields, offering improved tail behavior analysis.

Keywords:
Generalized gammaMittag-Leffler distributions

More Related Videos

Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.2K
Three-Dimensional Shape Modeling and Analysis of Brain Structures
05:33

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

6.6K

Related Experiment Videos

Last Updated: Apr 28, 2026

A Web Tool for Generating High Quality Machine-readable Biological Pathways
08:01

A Web Tool for Generating High Quality Machine-readable Biological Pathways

Published on: February 8, 2017

21.2K
Operation of the Collaborative Composite Manufacturing CCM System
10:09

Operation of the Collaborative Composite Manufacturing CCM System

Published on: October 1, 2019

6.2K
Three-Dimensional Shape Modeling and Analysis of Brain Structures
05:33

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

6.6K

Area of Science:

  • Mathematical and Stochastic Modeling
  • Data Analysis Across Scientific Disciplines

Background:

  • Existing models often struggle to capture complex data distributions.
  • The need for flexible modeling approaches that can adapt to diverse datasets is critical.

Purpose of the Study:

  • To examine mathematical and stochastic models capable of transitioning between different functional forms.
  • To demonstrate how pathway parameters enable capturing intermediate stages of distributions.
  • To provide a unified framework for selecting appropriate models across various scientific domains.

Main Methods:

  • Investigated a pathway of models including generalized beta (type-1 and type-2), generalized gamma, generalized Mittag-Leffler, and Lévy distributions.
  • Utilized pathway parameters to connect different families of functions.
  • Employed graphical representations to illustrate model behavior, including tail characteristics.

Main Results:

  • Demonstrated that pathway models can approximate data from biological, physical, engineering, and social sciences.
  • Showcased the ability of these models to capture transitional behaviors between established distributions.
  • Visualized how pathway parameters influence model properties such as tail thickness and right-tail cutoff.

Conclusions:

  • Flexible mathematical and stochastic models connected by pathway parameters offer a powerful tool for data analysis.
  • These models provide a means to find suitable approximations, even for complex or transitional data patterns.
  • The framework facilitates improved understanding of data characteristics through analysis of tail behaviors.