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Updated: Apr 28, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
Published on: February 16, 2016
The Big Picture: Evidence Base and Current Trials in Cardiac CT
Holger Hetterich1, Konstantin Nikolaou1, Maximilian F Reiser1
1Department of Clinical Radiology, Ludwig Maximilians University of Munich, Marchioninistrasse 15, 81377 Munich, Germany.
Abstract:
Cardiac computed tomography angiography (CCTA) has technically matured into a robust imaging modality for various cardiac disorders. Whereas early trials focused on assessment of the efficacy of CCTA in comparison with established recommended methods, current research efforts focus on the effectiveness of the technique in specific clinical scenarios. In this article, we provide an overview of recent technology advances, describe major clinical scenarios in which CCTA has been evaluated, and detail pertinent evidence from completed or ongoing clinical trials, including its use to investigate acute chest pain, its use among patients with stable chest pain syndrome, and its prognostic value for the occurrence of cardiovascular events.
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