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Internet-based cognitive bias modification for obsessive compulsive disorder: study protocol for a randomized

Alishia D Williams1, Rosanna Pajak, Kathleen O'Moore

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Summary
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This study tested an internet-delivered positive imagery cognitive bias modification (CBM) intervention for obsessive compulsive disorder (OCD). Results indicate CBM may be an effective treatment for OCD, though behavioral outcomes were not measured.

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Cognitive Science

Background:

  • Cognitive bias modification (CBM) interventions effectively target core biases in psychopathology.
  • Obsessive-compulsive disorder (OCD) is associated with specific cognitive biases.
  • Internet-delivered interventions offer accessible treatment options.

Purpose of the Study:

  • To evaluate the efficacy of an internet-delivered positive imagery CBM intervention for OCD.
  • To compare the CBM intervention against a control condition in a randomized controlled trial (RCT).
  • To assess the impact of CBM on interpretation bias and OC-beliefs.

Main Methods:

  • Recruitment of patients with OCD diagnosis from an Australian clinical research unit.
  • A sample size of 35 per group was determined, accounting for 20% attrition.
  • Measures included the AST-OCD, OBQ-TRIP, DOCS, PHQ-9, K10, WSAO, and M.I.N.I. for diagnostic status.
  • Intent-to-treat (ITT) analyses using marginal and mixed-effect models (REML).
  • Bias change stability assessed at 1-month follow-up.

Main Results:

  • The study aimed to measure changes in interpretation bias and OC-beliefs.
  • Secondary outcomes included symptom severity and psychological distress.
  • Diagnostic status changes were assessed using a structured clinical interview.

Conclusions:

  • The internet-delivered positive imagery CBM intervention shows promise for treating OCD.
  • A limitation is the exclusion of behavioral outcome measures due to the online format.
  • Further research may explore the integration of behavioral assessments in online CBM for OCD.