Related Experiment Video
Updated: Apr 28, 2026

Translationally-Relevant Tumor Resection Model for Murine Preclinical Models of Oral Squamous Cell Carcinoma
Published on: April 3, 2026
[Oropharyngeal cancer]
David Blanchard1, Jean-Pierre Rame1, Marie-Yolande Louis2
1CLCC François-Baclesse, Service d'ORL et de chirurgie cervico-faciale, 3, avenue du général Harris, 14076 Caen, France.
Abstract:
Oropharyngeal carcinomas, contrary to other head and neck carcinomas are of increasing frequency, mostly due to a frequent association with human papillomavirus infection. Pluridisciplinary management is necessary. New techniques as transoral surgery or intensity-modulated radiation therapy have the potential to reduce toxicities and morbidity while offering equivalent local control rates. Early stages may be treated with single modality treatment (surgery or radiotherapy) with five-year overall survival rate exceeding 80%. Advanced stages need therapeutic associations and five-years survival rates are inferior to 40%.
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