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Related Experiment Videos

Computer-assisted corneal topography in keratoconus.

Y S Rabinowitz1, P J McDonnell

  • 1Doheny Eye Institute, Los Angeles, CA 90033.

Refractive & Corneal Surgery
|November 1, 1989
PubMed
Summary
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Computer-assisted video-keratoscopy revealed distinct corneal topography patterns in keratoconus patients, showing significant differences in central power and inferior steepening compared to normal eyes.

Area of Science:

  • Ophthalmology
  • Corneal topography
  • Biomedical optics

Background:

  • Keratoconus is a progressive thinning disorder of the cornea.
  • Accurate topographic assessment is crucial for understanding keratoconus progression and management.
  • Previous studies may have been confounded by contact lens wear.

Purpose of the Study:

  • To characterize the corneal topographic findings in patients with keratoconus using computer-assisted video-keratoscopy.
  • To identify specific topographic patterns associated with keratoconus.
  • To quantitatively compare corneal parameters between keratoconus patients and normal eyes.

Main Methods:

  • Utilized a computer-assisted video-keratoscope to analyze corneal topography.
  • Examined 14 eyes from 10 patients diagnosed with keratoconus.

Related Experiment Videos

  • Excluded patients with recent contact lens wear to avoid topographical alterations.

    • Main Results:

    • Identified common patterns including inferior steepening (more temporal) and central steepening with an asymmetric bowtie pattern.
    • Found significant differences (p < 0.001) in central corneal power, fellow eye power difference, and inferior-superior corneal steepening compared to normal eyes.
    • Demonstrated the reliability of video-keratoscopy in detecting keratoconus-specific topographical changes.

    Conclusions:

    • Computer-assisted video-keratoscopy effectively visualizes characteristic topographic patterns in keratoconus.
    • Quantitative analysis reveals significant deviations in corneal power and steepness in keratoconus.
    • This technique offers valuable insights into anterior corneal surface changes and the pathogenesis of keratoconus.