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Published on: November 30, 2010
Age at presentation of common pediatric surgical conditions: Reexamining dogma
Jonathan Aboagye1, Seth D Goldstein1, Jose H Salazar1
1Center for Pediatric Surgical Clinical Trials & Outcomes Research, Division of Pediatric Surgery, Johns Hopkins University School of Medicine.
Insights
This study analyzed pediatric surgical conditions using national data. Ages for Hirschsprung disease, malrotation, and inguinal hernia presentation differ from common beliefs.
Area of Science:
- Pediatric Surgery
- Epidemiology
- Health Services Research
Background:
- Established ages of presentation for pediatric surgical conditions often lack robust, contemporary evidence.
- Reliance on single-center or outdated data may misrepresent disease epidemiology.
Purpose of the Study:
- To investigate the actual ages at presentation for common pediatric surgical conditions.
- To utilize large national databases for a more accurate epidemiological assessment.
Main Methods:
- Retrospective analysis of Healthcare Cost and Utilization Project (HCUP) databases (1988-2009).
- Identification of pediatric surgical conditions including malrotation, intussusception, hypertrophic pyloric stenosis (HPS), incarcerated inguinal hernia (IH), and Hirschsprung disease (HD) using ICD-9 codes.
- Descriptive statistical analysis of presentation ages.
Main Results:
- Analysis of 63,750 pediatric discharges.
- Malrotation: 58.2% presented before age 1.
- Hypertrophic pyloric stenosis (HPS): 92.8% presented between 3-10 weeks.
- Intussusception: 50.3% before age 1, 91.4% before age 4.
- Incarcerated Inguinal Hernia (IH): 55.8% before age 1.
- Hirschsprung disease (HD): 6.5% neonatal, 45.9% before age 1.
Conclusions:
- Findings validate commonly cited presentation ages for HPS and intussusception.
- Presentation ages for HD, malrotation, and IH in this cohort differ from established literature.
- Highlights the need to update epidemiological data for pediatric surgical conditions.
Purpose:
The commonly cited ages at presentation of many pediatric conditions have been based largely on single center or outdated epidemiologic evidence. Thus, we sought to examine the ages at presentation of common pediatric surgical conditions using cases from large national databases.
Methods:
A retrospective analysis was performed on Healthcare Cost and Utilization Project databases from 1988 to 2009. Pediatric discharges were selected using matched ICD9 diagnosis and procedure codes for malrotation, intussusception, hypertrophic pyloric stenosis (HPS), incarcerated inguinal hernia (IH), and Hirschsprung disease (HD). Descriptive statistics were computed.
Results:
A total of 63,750 discharges were identified, comprising 2744 cases of malrotation, 5831 of intussusception, 36,499 of HPS, 8564 of IH, and 10,112 of HD. About 58.2% of malrotation cases presented before age 1. Moreover, 92.8% of HPS presented between 3 and 10weeks. For intussusception, 50.3% and 91.4% presented prior to ages 1 and 4years, respectively. Also, 55.8% of IHD cases presented before their first birthday. For HD, 6.5% of cases presented within the neonatal period and 45.9% prior to age 1year.
Conclusion:
Our findings support generally cited presenting ages for HPS and intussusception. However, the ages at presentation for HD, malrotation, and IH differ from commonly cited texts.
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