Age at presentation of common pediatric surgical conditions: Reexamining dogma

Jonathan Aboagye1, Seth D Goldstein1, Jose H Salazar1

  • 1Center for Pediatric Surgical Clinical Trials & Outcomes Research, Division of Pediatric Surgery, Johns Hopkins University School of Medicine.

Insights

This study analyzed pediatric surgical conditions using national data. Ages for Hirschsprung disease, malrotation, and inguinal hernia presentation differ from common beliefs.

Area of Science:

  • Pediatric Surgery
  • Epidemiology
  • Health Services Research

Background:

  • Established ages of presentation for pediatric surgical conditions often lack robust, contemporary evidence.
  • Reliance on single-center or outdated data may misrepresent disease epidemiology.

Purpose of the Study:

  • To investigate the actual ages at presentation for common pediatric surgical conditions.
  • To utilize large national databases for a more accurate epidemiological assessment.

Main Methods:

  • Retrospective analysis of Healthcare Cost and Utilization Project (HCUP) databases (1988-2009).
  • Identification of pediatric surgical conditions including malrotation, intussusception, hypertrophic pyloric stenosis (HPS), incarcerated inguinal hernia (IH), and Hirschsprung disease (HD) using ICD-9 codes.
  • Descriptive statistical analysis of presentation ages.

Main Results:

  • Analysis of 63,750 pediatric discharges.
  • Malrotation: 58.2% presented before age 1.
  • Hypertrophic pyloric stenosis (HPS): 92.8% presented between 3-10 weeks.
  • Intussusception: 50.3% before age 1, 91.4% before age 4.
  • Incarcerated Inguinal Hernia (IH): 55.8% before age 1.
  • Hirschsprung disease (HD): 6.5% neonatal, 45.9% before age 1.

Conclusions:

  • Findings validate commonly cited presentation ages for HPS and intussusception.
  • Presentation ages for HD, malrotation, and IH in this cohort differ from established literature.
  • Highlights the need to update epidemiological data for pediatric surgical conditions.
Abstract

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