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Updated: Apr 28, 2026

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
Published on: August 11, 2008
Multidrug-resistant and extensively drug-resistant tuberculosis: a review of current concepts and future challenges
1Division of Clinical Infectious Diseases, Medical Clinic, Research Center Borstel, Borstel, Germany, and Department of Medicine, University of Namibia School of Medicine, Windhoek, Namibia gguenther@fz-borstel.de.
Abstract:
Multidrug-resistant and extensively drug-resistant tuberculosis are recent global health issues, which makes tuberculosis - after the success of short course treatment during the second half of the last century - a major health challenge. Globalisation, health inequalities, competing economic interests and political instability contribute substantially to the spread of drug-resistant strains, which are associated with high rates of morbidity and mortality. Issues such as increasing transmission of drug-resistant strains, poor diagnostic coverage and a lengthy, toxic treatment need to be overcome by innovative approaches to tuberculosis control, prevention, diagnostics and treatment. This review addresses recent developments and future concepts.
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