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Association between alcohol consumption and systolic ventricular function: a population-based study.

Haroon Yousaf1, Richard J Rodeheffer2, Timothy E Paterick1

  • 1Aurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke's Medical Centers, University of Wisconsin School of Medicine and Public Health, Milwaukee, WI.

American Heart Journal
|June 4, 2014
PubMed
Summary
This summary is machine-generated.

Light alcohol consumption shows a U-shaped relationship with left ventricular systolic dysfunction, with the lowest risk observed in light drinkers. Heavy drinking increases the risk of moderate systolic dysfunction.

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Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Moderate alcohol intake is linked to reduced clinical heart failure.
  • Population-based data on alcohol consumption and left ventricular (LV) systolic function are limited.
  • This study investigates the community-level relationship between alcohol intake and LV systolic function.

Purpose of the Study:

  • To evaluate the association between alcohol consumption patterns and left ventricular systolic function.
  • To identify specific drinking levels associated with altered systolic function.
  • To understand the community prevalence of alcohol-related systolic dysfunction.

Main Methods:

  • A population-based random sample of 2,042 adults aged 45+ was surveyed.
  • Alcohol consumption was self-reported and categorized (abstainer, former, light, moderate, heavy).
  • Left ventricular systolic function was assessed using echocardiography.

Main Results:

  • A U-shaped relationship was found between alcohol consumption and moderate systolic dysfunction (LV ejection fraction ≤40%).
  • Light drinkers (<1 drink/day) had the lowest prevalence (0.9%), while heavy drinkers (>2 drinks/day) had the highest (5.5%).
  • This association remained significant after adjusting for risk factors and in multivariate analysis.

Conclusions:

  • A U-shaped relationship exists between alcohol consumption volume and LV ejection fraction.
  • Light alcohol consumption is associated with the lowest risk of moderate LV dysfunction.
  • Findings parallel the known relationship between alcohol intake and cardiovascular disease prevalence.