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Related Experiment Video

Updated: Apr 28, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
18:50

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

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[The MitraClip procedure].

Alec Vahanian1, Dominique Himbert1, Eric Brochet1

  • 1Hôpital Bichat, université Paris VII, département de cardiologie, service de chirurgie cardiaque, 75018 Paris, France.

Presse Medicale (Paris, France : 1983)
|June 4, 2014
PubMed
Summary

Mitral insufficiency, a common heart valve disease, can be treated with the MitraClip procedure for high-risk patients. While less effective than surgery, it offers mid-term functional improvement and good safety in experienced centers.

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Articles linked to this work by shared authors, journal, and citation graph.

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Survival outcomes in isolated severe tricuspid regurgitation according to therapeutic modalities: a systematic review and meta-analysis.

Open heart·2025
Same author

Hospitalization of Symptomatic Patients With Heart Failure and Moderate to Severe Functional Mitral Regurgitation Treated With MitraClip: Insights From RESHAPE-HF2.

Journal of the American College of Cardiology·2024
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Transcatheter Valve Repair in Heart Failure with Moderate to Severe Mitral Regurgitation.

The New England journal of medicine·2024
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Sex-related differences in severe native valvular heart disease: the ESC-EORP Valvular Heart Disease II survey.

European heart journal·2024
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Management of Massive Thrombosis of a Tendyne Valve: The Importance of Heart Valve Centers.

JACC. Case reports·2024
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Percutaneous repair of moderate-to-severe or severe functional mitral regurgitation in patients with symptomatic heart failure: Baseline characteristics of patients in the RESHAPE-HF2 trial and comparison to COAPT and MITRA-FR trials.

European journal of heart failure·2024

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Cardiac Surgery

Context:

  • Mitral insufficiency is a prevalent valvular heart disease.
  • Surgical mitral valve repair is the standard treatment.
  • Many patients are high-risk surgical candidates due to comorbidities.

Purpose:

  • To evaluate the MitraClip procedure as an alternative for mitral valve repair.
  • To assess the safety, efficacy, and mid-term outcomes of the MitraClip procedure.
  • To identify patient populations who may benefit from this minimally invasive approach.

Summary:

  • The MitraClip procedure offers a less invasive option for mitral valve repair, particularly for patients unsuitable for surgery.
  • While achieving a lesser degree of mitral insufficiency reduction compared to surgery, it demonstrates good safety in experienced centers and provides mid-term functional improvement.

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  • Current evidence, primarily from registries with limited follow-up, suggests its consideration for symptomatic high-risk patients on optimal medical therapy.

    • Impact:

    • Provides a viable treatment option for high-risk patients with mitral insufficiency.
    • Highlights the need for further research, including randomized trials and longer follow-up, to refine the technique and equipment.
    • Suggests potential for future advancements in percutaneous combined procedures for valvular heart disease.