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Second-generation ALK inhibitors: filling the non "MET" gap

Suresh S Ramalingam1, Fadlo R Khuri2

  • 1Authors' Affiliation: Department of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, Georgia.

Cancer Discovery
|June 4, 2014
PubMed
Summary

Second-generation inhibitors like ceritinib show promise against anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC). These drugs overcome resistance mutations, offering new treatment options for ALK-positive NSCLC patients.

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