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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
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Related Experiment Video

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Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
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Squamous cell carcinoma: morphological & topographical spectrum: a two year analysis.

Sanjeev Narang1, Namrata Kanungo1, Ravi Jain1

  • 1Department of Pathology, M.G.M Medical College, A.B. Road, Indore, PIN 452001 M.P. India.

The Indian Journal of Surgery
|June 4, 2014
PubMed
Summary
This summary is machine-generated.

Squamous cell carcinoma (SCC) is a common cancer globally. This study analyzed 959 SCC cases from 2007-2008 in Indore, India, finding it most prevalent in the lip, oral cavity, and pharynx.

Keywords:
Carcinoma in situICD-OMorphologic categoriesSquamous cell carcinomaSquamous epitheliumTopographic spectrum

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Area of Science:

  • Oncology
  • Pathology
  • Cancer Research

Background:

  • Squamous cell carcinoma (SCC) is a significant global cause of cancer-related morbidity and mortality.
  • It is a prevalent cancer in India, affecting both men and women.

Purpose of the Study:

  • To analyze the spectrum of SCC cases presenting at M.Y. Hospital, Indore, between 2007 and 2008.
  • To understand the morphological patterns and anatomical site distribution of SCC lesions.
  • To classify these lesions according to the International Classification of Diseases for Oncology (ICD-O, third edition).

Main Methods:

  • Retrospective analysis of 959 histopathology-confirmed SCC cases.
  • Data collected from the M.Y. Hospital, Indore, over a 2-year period (2007-2008).
  • Classification of SCC based on morphology and topographical site using ICD-O criteria.

Main Results:

  • The majority of SCC cases (30.24%) occurred between the fourth and fifth decades of life, with 96.35% of patients older than 30 years.
  • Invasive SCC accounted for 94.3% of cases, with distant metastasis in 4.7% and in situ/noninvasive types in 1%.
  • The most common sites were the lip, oral cavity, and pharynx (56.50%), followed by female genital organs (30.24%). ICD-O category C-53 (cervix) was most frequent (26.07%), and keratinizing squamous cell carcinoma was the predominant morphological type (35.2%).

Conclusions:

  • SCC predominantly affects individuals over 30 years old, with a high incidence in the lip, oral cavity, and pharynx.
  • Invasive and keratinizing types are the most common morphological presentations.
  • The findings highlight the importance of anatomical site and morphological classification for understanding SCC patterns in the Indian population.