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Intracranial Orthotopic Allografting of Medulloblastoma Cells in Immunocompromised Mice
Published on: October 3, 2010
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Atypical medulloblastoma: A case series
Ali Meshkini1, Amir Vahedi2, Mohammad Meshkini3
1Neuroscience Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Asian Journal of Neurosurgery
|June 4, 2014
Summary
Medulloblastoma, a common pediatric posterior fossa tumor, often presents atypically. Clinicians should consider medulloblastoma in midline posterior fossa masses, even with features suggesting other conditions, requiring histologic confirmation.
Area of Science:
- Neuro-oncology
- Pediatric oncology
- Neuroradiology
Background:
- Medulloblastoma is a common pediatric tumor originating in the midline posterior fossa (vermis).
- Typical medulloblastoma presents with a characteristic clinic-radiological pattern: a homogeneously enhancing hyperdense mass on CT and posterior fossa syndrome.
- A significant number of medulloblastoma cases, in both children and adults, exhibit atypical or uncommon clinic-radiological features.

