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Updated: Apr 28, 2026

Compact Quantum Dots for Single-molecule Imaging
Published on: October 9, 2012
Enhanced chemiluminescence CdSe quantum dots by histidine and tryptophan
Morteza Hosseini1, Mohammad Reza Ganjali2, Afsaneh Jarrahi3
1Department of Life Science Engineering, Faculty of New Sciences & Technologies, University of Tehran, Tehran, Iran.
Abstract:
The enhancing effect of histidine and tryptophan on chemiluminescence (CL) of CdSe quantum dots (QDs)-H2O2 system was studied. This reaction is based on the catalytic effect of amino acids, causing a significant increase in the light emission, as a result of the reaction of quantum dots (QDs) with hydrogen peroxide. In the optimum conditions, this method was satisfactorily described by linear calibration curve in the range of 0.66-35.5 μM and 0.83-35.1 μM for histidine and tryptophan, respectively. The effect of various parameters such as concentration of CdSe QDs, concentration of H2O2 and concentration of imidazole on the intensity of CL system were studied. The main experimental advantage of the proposed method is it's selective to two amino acids compared with other amino acids.
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