Invasive validation of the Complior Analyse in the assessment of central artery pressure curves: a methodological
Telmo Pereira1, João Maldonado, Rita Coutinho
1aPolytechnic Institute of Coimbra, ESTES, Department of Cardiopneumology bInstitute of Cardiovascular Research, Coimbra, Portugal.
Insights
The Complior Analyse device accurately measures carotid pressure waves, offering a reliable noninvasive method for arterial function analysis in clinical practice. This study confirms its precision in evaluating cardiovascular health.
Area of Science:
- Cardiovascular Physiology
- Medical Device Technology
Background:
- Arterial function is critical in cardiovascular diseases.
- Studying arterial function is essential for clinical practice.
Purpose of the Study:
- To evaluate the accuracy of the new Complior Analyse device for carotid pulse wave analysis.
Main Methods:
- Cross-sectional study with 15 patients undergoing cardiac catheterization.
- Simultaneous measurement of pressure curves in the ascending aorta (invasive) and carotid artery (Complior Analyse).
- Comparison of central arterial pressures, augmentation indexes, and wave morphology.
Main Results:
- Excellent concordance between Complior Analyse and invasive measurements (ICC > 0.9).
- Bland-Altman analysis showed small mean differences and good accuracy.
- Strong Pearson correlations (r² > 0.92) confirmed accuracy, independent of patient characteristics.
Conclusions:
- The Complior Analyse device accurately measures carotid pressure waves.
- It serves as a simple, reliable, and noninvasive alternative for pressure wave analysis.
Introduction:
Arteries are the target, the place, and the common denominator of cardiovascular diseases; hence, study of arterial function is of greatest importance in clinical practice. The aim of this study was to evaluate the accuracy of carotid pulse wave analysis using the new version of the Complior device--the Complior Analyse.
Methods And Results:
This was a cross-sectional study that included 15 patients (seven women), mean age 62.07±10.59 years, referenced for cardiac catheterization. Pressure curves were obtained simultaneously in the ascending aorta (invasively) and in the right common carotid artery (using the Complior Analyse). Mean central arterial pressures, augmentation indexes, and wave morphology obtained using both methods were compared. A good concordance between methods was obtained for all the parameters measured, with intraclass correlation coefficients above 0.9. Bland-Altman analysis also indicated a good accuracy profile of the Complior device, with small mean differences observed for all parameters and most values confined within 2 SD of the mean difference. This was further confirmed by the strong Pearson correlation coefficients, with r² coefficients above 0.92 for all the variables studied. The correlations observed were independent of sex, age, arterial pressure, and BMI.
Conclusion:
The results presented and available research clearly indicate that the Complior Analyse device measures carotid pressure waves accurately; therefore, it is a simple and reliable noninvasive alternative for pressure wave analysis.
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