Related Experiment Video
Updated: Apr 28, 2026

Continuous Venous-Arterial Doppler Ultrasound During a Preload Challenge
Published on: January 20, 2023
Should we stop using the determination of central venous pressure as a way to estimate cardiac preload?
Johann Smith Cerón Arias1, Manuel Felipe Muñoz Nañez2
1Universidad del Cauca Email johanceron@gmail.com.
Insights
Central venous pressure is questioned for assessing cardiac preload. While other methods like end-diastolic volume are more accurate, central venous pressure remains a practical choice, though dynamic variables offer superior blood volume assessment.
Area of Science:
- Critical Care Medicine
- Hemodynamics
- Cardiology
Background:
- Central venous pressure (CVP) has historically guided fluid resuscitation in critical patients.
- Its efficacy in measuring cardiac preload is increasingly debated.
- This has spurred interest in more precise preload and blood volume assessment methods.
Purpose of the Study:
- To evaluate the effectiveness of central venous pressure (CVP) in determining cardiac preload.
- To review current literature on hemodynamic monitoring parameters.
Main Methods:
- Literature review of studies assessing cardiac preload and fluid responsiveness.
- Analysis of parameters including central venous pressure, ventricular dimensions, and dynamic variables.
Main Results:
- End-diastolic ventricular area and global end-diastolic volume demonstrate superior performance over CVP for preload assessment.
- Central venous pressure is still widely used due to its practicality and availability.
- Dynamic variables, such as pulse pressure variation, show greater accuracy in assessing individual blood volume.
Conclusions:
- Current evidence suggests limitations in using central venous pressure for accurate cardiac preload assessment.
- Alternative methods offer improved accuracy but may lack the practicality of CVP.
- Dynamic hemodynamic parameters represent the most effective approach for evaluating fluid status and guiding therapy.
Introduction:
The determination of the values of central venous pressure has long been used as a guideline for volumetric therapy in the resuscitation of the critical patient, but the performance of such parameter is currently being questioned as an effective measurement of cardiac preload. This has aroused great interest in the search for more accurate parameters to determine cardiac preload and a patient's blood volume.
Goals And Methods:
Based on literature currently available, we aim to discuss the performance of central venous pressure as an effective parameter to determine cardiac preload.
Results And Conclusion:
Estimating variables such as end-diastolic ventricular area and global end-diastolic volume have a better performance than central venous pressure in determining cardiac preload. Despite the best performance of these devices, central venous pressure is still considered in our setting as the most practical and most commonly available way to assess the patient's preload. Only dynamic variables such as pulse pressure change are superior in determining an individual's blood volume.
Related Concept Videos
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Pulse
Pulse Rate and its Significance
Pulse rate, often measured in beats per minute (bpm), reflects the heart rate (HR), which is influenced by numerous factors such as stress, physical activity, and hormonal changes. A normal resting adult pulse rate falls...
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac...
Cardiac Catheterization II: Right Heart Catheterization
Regulation of Stroke Volume
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...

