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Published on: October 6, 2016
Effect of exercise on cardiac and metabolic outcomes in people living with HIV
Insights
Exercise may help people with HIV manage cardiovascular disease risk factors. This review examines aerobic and resistance training impacts on metabolic and heart health in people living with HIV (PLWH).
Area of Science:
- Cardiology
- Infectious Diseases
- Exercise Science
Background:
- Poorly controlled HIV infection and antiretroviral therapy, particularly protease inhibitors, increase cardiovascular disease (CVD) risk in people living with HIV (PLWH).
- Lifestyle factors (smoking, inactivity, poor diet) and psychosocial elements (stress, trauma, depression) exacerbate CVD risk in PLWH.
Purpose of the Study:
- To critically evaluate recent aerobic and resistance exercise studies.
- To assess the impact of exercise on cardiovascular and metabolic risk factors in PLWH.
Main Methods:
- Systematic review of recent exercise intervention studies.
- Analysis of cardiovascular and metabolic outcomes in people living with HIV.
Main Results:
- Emerging evidence suggests exercise interventions can positively influence CVD risk factors in PLWH.
- Specific impacts on lipid profiles, inflammation, and body composition require further investigation.
Conclusions:
- Aerobic and resistance exercise show promise for mitigating cardiovascular and metabolic risks in people living with HIV.
- Further research is needed to optimize exercise protocols and long-term benefits for PLWH.
Abstract:
Poorly controlled HIV infection and antiretroviral therapy, especially the use of protease inhibitors, are among the causes that contribute to the development of cardiovascular disease in people living with HIV (PLWH). Poor lifestyle choices (smoking, lack of physical activity, poor diet) and individual factors such as high stress, physical or emotional trauma, depression, and so forth contribute to the overall risk of developing cardiovascular disease. The purpose of this review was to critically evaluate the more recent aerobic and resistance exercise studies and their impact on cardiovascular and metabolic risk factors in PLWH.
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