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Synthesis of two new hydroxylated derivatives of spironolactone by microbial transformation

Jianfeng Mei1, Luoyi Wang2, Siyuan Wang2

  • 1Department of Biological Engineering, Utah State University, 4105 Old Main Hill, Logan, UT 84322, United States; College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, Zhejiang 310032, China.

Bioorganic & Medicinal Chemistry Letters
|June 5, 2014
PubMed

Keywords:
BiotransformationCunninghamella elegansSelective hydroxylationSpironolactone

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