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Thermal Ablation for the Treatment of Abdominal Tumors
Published on: March 7, 2011
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CT-guided radiofrequency tumor ablation in children
Evanthia Botsa1, Loukia S Poulou, Ioannis Koutsogiannis
1First Pediatric Clinic, Agia Sofia Children's Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Pediatric Radiology
|June 5, 2014
Summary
CT-guided radiofrequency ablation is a safe and effective treatment for pediatric metastatic neoplasms. This minimally invasive technique achieved total tumor necrosis in all patients, with no major complications reported.
Area of Science:
- Pediatric oncology
- Interventional radiology
- Minimally invasive cancer treatment
Background:
- Image-guided radiofrequency ablation is established for adult interventional oncology.
- Pediatric applications require evaluation for efficacy and safety.
Purpose of the Study:
- To assess CT-guided radiofrequency ablation for treating pediatric metastatic neoplasms.
- Evaluate safety and efficacy in a pediatric cohort.
Main Methods:
- 15 CT-guided radiofrequency ablation sessions in 12 pediatric patients (5-18 years) with metastatic disease.
- Targeted lesions included hepatic, pulmonary, and bone metastases.
- Procedures performed under conscious sedation.
Main Results:
- Successful ablation in all tumors, with median lesion size 1.7 cm and ablation time 8 min.
- Complete tumor necrosis observed on imaging at 1 and 3 months post-ablation.
- Four children experienced post-ablation syndrome; no major complications. Local recurrence in 3 patients with larger lesions (>2 cm) at 6 months, treated successfully with repeat ablation. No recurrence at 2-year follow-up.
Conclusions:
- CT-guided radiofrequency tumor ablation is a safe and efficient palliative treatment for pediatric metastatic neoplasms.
- Demonstrates high technical success and efficacy in achieving tumor necrosis.
- Low complication rate supports its use in pediatric oncology.
