[Merkel cell carcinoma in primary care]

Area of Science:

• Dermatology
• Oncology
• Pathology

Background:

• Merkel cell carcinoma (MCC) is a rare, aggressive skin cancer originating from neuroendocrine cells.
• MCC predominantly affects individuals over 50, particularly women, and is often found in sun-exposed skin.
• The neoplasm is characterized by rapid growth, high recurrence rates, and frequent metastasis to skin and lymph nodes.

Observation:

• A clinical case involving a 76-year-old woman presented with a persistent, non-responsive erythematous nodule on her right forearm.
• The lesion's characteristics and lack of response to initial treatments raised suspicion for a rare cutaneous malignancy.
• Diagnostic evaluation was crucial to identify the underlying cause of the persistent skin lesion.

Findings:

• The final diagnosis confirmed the presence of Merkel cell carcinoma.
• The patient received treatment for the Merkel cell tumour.
• Post-treatment follow-up indicated a positive clinical response and good progress.

Implications:

• This case underscores the importance of vigilant diagnosis and timely intervention for suspected Merkel cell carcinoma.
• Effective management strategies, though debated, can lead to favorable outcomes in MCC patients.
• Further research into optimal treatment protocols for Merkel cell carcinoma is warranted to improve patient survival and quality of life.