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Published on: December 11, 2017
Surgical treatment of aortic valve endocarditis: a 26-year experience
Taylan Adademir1, Eylem Yayla Tuncer1, Serpil Tas1
1Department of Cardiovascular Surgery, Kartal Kosuyolu Heart and Research Hospital, Istanbul, Turkey.
Insights
Surgery for aortic valve endocarditis has significant mortality, with emergency operations and female gender being key risk factors. While recurrence risk is low, understanding these factors is crucial for patient outcomes.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Clinical Outcomes Research
Background:
- Aortic valve endocarditis is a serious condition requiring surgical intervention.
- Long-term outcomes and risk factors for aortic valve endocarditis surgery are critical to understand.
Purpose of the Study:
- To retrospectively analyze surgical outcomes for aortic valve endocarditis over 26 years.
- To identify risk factors associated with in-hospital and long-term mortality, as well as recurrence.
Main Methods:
- Retrospective analysis of 174 patients operated for aortic valve endocarditis between 1985 and 2011.
- Data collection included patient demographics, procedure types, in-hospital complications, and long-term follow-up.
- Statistical analysis identified factors associated with mortality and recurrence.
Main Results:
- Aortic valve replacement with mechanical prosthesis was the most common procedure (81.6%).
- In-hospital mortality was 15.5%, associated with female gender, emergency surgery, renal failure, and low cardiac output.
- Long-term mortality was linked to mitral valve involvement; male gender was a risk factor for recurrence.
Conclusions:
- Aortic valve endocarditis surgery carries significant mortality and morbidity.
- Emergency operations, female gender, postoperative renal failure, and low cardiac output are identified as critical risk factors.
- The risk of recurrence and reoperation is notably low.
Objective:
We have retrospectively analyzed the results of the operations made for aortic valve endocarditis in a single center in 26 years.
Methods:
From June 1985 to January 2011, 174 patients were operated for aortic valve endocarditis. One hundred and thirty-eight (79.3%) patients were male and the mean age was 39.3±14.4 (9-77) years. Twenty-seven (15.5%) patients had prosthetic valve endocarditis. The mean duration of follow-up was 7.3±4.2 years (0.1-18.2) adding up to a total of 1030.8 patient/years.
Results:
Two hundred and eighty-two procedures were performed. The most frequently performed procedure was aortic valve replacement with mechanical prosthesis (81.6%). In-hospital mortality occurred in 27 (15.5%) cases. Postoperatively, 25 (14.4%) patients had low cardiac output and 17 (9.8%) heart block. The actuarial survival rates for 10 and 15 years were 74.6±3.7% and 61.1±10.3%, respectively. In-hospital mortality was found to be associated with female gender, emergency operation, postoperative renal failure and low cardiac output. The long term mortality was significantly associated with mitral valve involvement. Male gender was found to be a significant risk factor for recurrence in the follow-up.
Conclusion:
Surgery for aortic valve endocarditis has significant mortality. Emergency operation, female gender, postoperative renal failure and low cardiac output are significant risk factors. Risk for recurrence and need for reoperation is low.
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