Related Experiment Video
Updated: Apr 28, 2026

Sucrose Preference and Novelty-Induced Hypophagia Tests in Rats using an Automated Food Intake Monitoring System
Published on: May 8, 2020
Instrumental performance following saccharin pre-feeding
1Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge CB2 3EB, England.
Pre-feeding rats with saccharin depressed instrumental performance after variable ratio schedule training but not after variable interval training. This suggests pre-feeding effects on motivation are incentive-based, not drive-based.
Area of Science:
- Behavioral neuroscience
- Animal learning theory
Background:
- Instrumental performance is influenced by motivational states.
- Pre-feeding effects on behavior are complex and depend on training parameters.
Purpose of the Study:
- To investigate how pre-feeding with a non-nutritive substance affects instrumental performance under different reinforcement schedules.
- To differentiate between incentive and drive mechanisms in mediating pre-feeding effects.
Main Methods:
- Two experiments were conducted with rats.
- Instrumental performance was trained using variable ratio and variable interval schedules.
- Pre-feeding involved a saccharin solution, followed by extinction testing.
Main Results:
- Pre-feeding with saccharin significantly depressed instrumental performance following variable ratio schedule training.
- Instrumental performance remained unaffected by saccharin pre-feeding after variable interval schedule training.
Conclusions:
- The impact of pre-feeding on instrumental performance is dependent on the reinforcement schedule.
- Motivational effects of non-nutritive pre-feeding appear to operate via an incentive process rather than a drive process.
More Related Videos
08:07Simultaneous Detection of c-Fos Activation from Mesolimbic and Mesocortical Dopamine Reward Sites Following Naive Sugar and Fat Ingestion in Rats
Published on: August 24, 2016
11:16A Novel Procedure for Evaluating the Reinforcing Properties of Tastants in Laboratory Rats: Operant Intraoral Self-administration
Published on: February 6, 2014