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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
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Obesity and periodontitis: systematic review and meta-analysis
Ciencia & Saude Coletiva
|June 5, 2014
Summary
Obesity is linked to a higher risk of periodontitis, according to a systematic review. Further research is needed to clarify the exact relationship and contributing risk factors for these conditions.
Area of Science:
- Oral Health
- Public Health
- Epidemiology
Background:
- Periodontitis is a common oral disease.
- Obesity is a growing global health concern.
- The association between obesity and periodontitis requires further investigation.
Purpose of the Study:
- To systematically review and meta-analyze studies on the association between obesity and periodontitis.
- To determine if obesity is a risk factor for periodontitis.
Main Methods:
- Systematic literature search of PubMed, Embase, and Lilacs databases up to 2010.
- Inclusion and exclusion criteria applied to select human studies.
- Meta-analysis of 31 selected studies.
Main Results:
- A significant association was found between obesity and periodontitis (OR = 1.30, 95% CI: 1.25-1.35).
- A positive association was observed between mean Body Mass Index (BMI) and periodontal disease (mean difference = 2.75).
- Of 31 studies, 25 indicated an association, while 6 did not.
Conclusions:
- Obesity is associated with an increased risk of periodontitis.
- Further research is needed to clarify aggravating risk factors and the directionality of the association.
- Homogeneity in future studies can be improved by using paired samples and controlling for confounding factors.
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