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Published on: March 31, 2023
Aortic valve disease
1Department of Cardiology, Oxford University Hospitals NHS Trust, Oxford, UK.
Insights
Aortic valve diseases like stenosis and regurgitation significantly impact patient health. This review covers their causes, diagnosis, and treatments, including transcatheter aortic valve implantation (TAVI).
Area of Science:
- Cardiology
- Cardiovascular Surgery
- Medical Education
Background:
- Aortic valve disease, including aortic stenosis (AS) and aortic regurgitation (AR), is prevalent and affects patient prognosis and quality of life.
- Understanding the pathophysiology, presentation, and assessment of these conditions is crucial for effective management.
Purpose of the Study:
- To provide an educational review of aortic stenosis and regurgitation.
- To discuss current and emerging treatment strategies, including transcatheter aortic valve implantation (TAVI) and novel surgical approaches.
Main Methods:
- Review of current literature on aortic valve disease.
- Analysis of diagnostic modalities, including advanced imaging beyond echocardiography.
- Evaluation of treatment strategies, focusing on TAVI indications and surgical options.
Main Results:
- Aortic stenosis and regurgitation require comprehensive assessment using various imaging techniques.
- Transcatheter aortic valve implantation (TAVI) is an emerging option for AS patients unsuitable for conventional aortic valve replacement (AVR).
- Novel surgical techniques and future percutaneous interventions are being developed for AR.
Conclusions:
- Effective management of aortic valve disease necessitates a thorough understanding of its multifaceted aspects.
- TAVI represents a significant advancement in treating AS, expanding treatment options for specific patient groups.
- Ongoing research promises further innovations in surgical and percutaneous treatments for aortic regurgitation.
Abstract:
Aortic valve disease is common and has significant impact on prognosis and quality of life. In this educational review, we cover the pathophysiology, presentation and assessment of aortic stenosis (AS) and aortic regurgitation (AR), including the role of imaging modalities beyond echocardiography. We review current treatment strategies and emphasise the use and indications for transcatheter aortic valve implantation (TAVI) in view of recent data highlighting its emergence as a novel treatment option for patients with AS, who are unsuitable for conventional aortic valve replacement (AVR). We also describe novel surgical approaches for AR and potential future strategies for percutaneous intervention.
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