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Real-Time Monitoring of Aurora kinase A Activation using Conformational FRET Biosensors in Live Cells
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Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core

Tao Yu1, Jayaram R Tagat1, Angela D Kerekes1

  • 1Departments of Chemical Research.

ACS Medicinal Chemistry Letters
|June 6, 2014
PubMed

Keywords:
Aurora kinase inhibitorsSCH 1473759aqueous solubilitycell potencyimidazo-[1,2-a]-pyrazinetumor xenograft model

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