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Discovery and Structural Modification of 1-Phenyl-3-(1-phenylethyl)urea Derivatives as Inhibitors of Complement

Mei Zhang1, Xiao-Ying Yang2, Wei Tang2

  • 1Department of Chemistry and Institute of Medicinal Chemistry, East China Normal University , 3663 North Zhong Shan Road, Shanghai 200062, People's Republic of China ; Chinese National Center for Drug Screening, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 189 Guoshoujing Road, Zhangjiang Hi-Tech Park, Shanghai 201203, People's Republic of China.

ACS Medicinal Chemistry Letters
|June 6, 2014
PubMed

Keywords:
C9complement inhibitorshigh-throughput screeningstructural modification

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