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Getting the MAX out of Computational Models: The Prediction of Unbound-Brain and Unbound-Plasma Maximum

Scot Mente1, Angela Doran1, Travis T Wager1

  • 1Groton Laboratories, Pfizer Worldwide Research and Development , 1 Eastern Point Road, Groton, Connecticut 06340, United States.

ACS Medicinal Chemistry Letters
|June 6, 2014
PubMed

Keywords:
ADMECmaxblood–brain barrierbrain availabilityfraction unboundvolume of distribution

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